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SGLT2 inhibitors mitigate renal NLRP3 inflammasome activation, which is hyperstimulated in diabetic kidneys, thereby decreasing IL-1 and IL-18 secretion from macrophages (94)
Maintaining natural growth hormone rhythm supports recovery processes, metabolic balance, and cellular repair during sleep
Additional research is exploring its role in angiogenic signaling, cellular turnover, and oxidative stress response pathways
Comment: A few commenters supported the proposal to maintain technical specifications for MIPS measures in ASM, because this is more cost-effective and efficient than developing and maintaining separate measures for ASM and MIPS