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Collectively, these findings indicate that a combined approach utilizing pharmacological (NAC) and psychosocial (EE) interventions, even when implemented following an initial insult, has the potential to reverse persistent impairments in PVI/perineuronal net integrity, thereby presenting a promising new therapeutic strategy for individuals at risk of early-life neurodevelopmental adversities

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Regiani T, Cordeiro FB, da Costa L do VT, Salgueiro J, Cardozo K, Carvalho VM, et al

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