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IGF-1 is double-edged when it comes to our health, with the potential to provide much benefit or harm: too little, and we do not develop properly, we lose muscle mass, bone strength diminishes, and our cognition declines as we age

Clinical studies have shown that retatrutide, as an adjunct therapy, significantly lowers HbA1c levelsa key marker of long-term blood sugar control

That's not really the study question

Why Hydration Becomes Harder on GLP-1 Drugs Many athletes on GLP-1 medications also report reduced thirst sensation

5 This is an impressive feat given the significant reduction in force across the agency in the spring of 2025