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Important safety information: Tirzepatide has a boxed warning for risk of thyroid C-cell tumors and is contraindicated in patients with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2 (MEN2)

Diagnosis is aided with the use of dermoscopy and less commonly reflectance confocal microscopy

Blood work showing estradiol levels guides decision-making

seek medical help promptly if these occur Gallbladder symptoms : Be alert for signs of gallstones or cholecystitis (severe upper abdominal pain, particularly after meals) Pancreatitis symptoms : Seek immediate medical attention for severe, persistent abdominal pain radiating to the back Managing common gastrointestinal side effects: Follow the gradual dose escalation schedule (starting at 0.6 mg daily, increasing weekly by 0.6 mg increments to the maintenance dose of 3.0 mg)

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