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In preclinical models, DSIP is applied to investigate how peptide signaling contributes to stress adaptation, neuroendocrine balance, and systemic homeostasis under varying physiological conditions

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In studies where beta-3 receptors were genetically deleted, AOD-9604 lost its fat-reducing effects, confirming the critical role of this pathway

One such compound, epithalamin, was found to be a complex peptide bioregulator that could reduce the rate of cellular aging, leading to increased longevity