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It has been noted that Chinese larynx cancer patients have a higher prevalence of HPV and that HPV infection significantly increases the risk of larynx cancer compared to larynx cancer patients outside of China 28

The genetic variants are no more common among smokers than non-smokers

(2021) MMWR Morb Mortal Wkly Rep, 70: 1183

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Ethmoid or frontal sinusitis can cause a blood clot in the sinus area around the front and top of the face