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Nausea, jaundice, dark urine, pale stool, severe abdominal pain, confusion, swelling or rapidly worsening fatigue require medical evaluation rather than more supplements or fasting

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Certain -blockers, particularly nonselective -blockers, may be associated with adverse effects on glucose metabolism and insulin sensitivity, potentially leading to an increased risk of developing or exacerbating diabetes (Tomiyama and Yamashina, 2014)

[DOI] [PubMed] [Google Scholar] Ly JQ, Messick K, Qin A, Takahashi RH, and Choo EF (2017) Utility of CYP3A4 and PXR-CAR-CYP3A4/3A7 Transgenic Mouse Models To Assess the Magnitude of CYP3A4 Mediated Drug-Drug Interactions