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In other words, you can take vitamin B12 at any time that you find convenient

Optional B-12 Supplementation: Vitamin B-12 supplementation is included as an optional add-on at no additional charge

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Unfortunately, there have not been any large controlled studies on the topic of how GLP-1 medications like semaglutide and tirzepatide affect menstrual cycles in women who do not have PCOS, so we just do not have enough data to make a solid determination of the effects of GLP-1s on menstruation