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Patients should be informed of the pros and cons of oral versus parenteral therapy, and regardless of the form of treatment, those with pernicious anemia or malabsorption should be reminded of the need for lifelong replacement

Probably the improvement in glucose homeostasis contributed to a higher survival rate in animals treated with the QV formulation than untreated diabetic rats and diabetic rats treated with a daily dose of insulin, suggesting that the treatment with formulation may be associated with a low risk of the hypoglycemia that sometimes results from insulin administration 15

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