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While both drugs target appetite and metabolic regulation through different pathways, limited clinical data exists on their simultaneous use, making informed decision-making essential before pursuing this approach

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It was shown that cRGD, H-ferritin, angiopoietin-2, apolipoprotein A1, and lactoferrin can all be conjugated to nanoparticles, thereby promoting their permeability to the BBB[152,153,154,155,156,157]

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