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Depressant Addiction Depressants are a class of drugs that reduce arousal and stimulation in the user, affecting the central nervous system (CNS) by slowing down brain function and enhancing the production of a neurotransmitter called gamma-aminobutyric acid (GABA)

Those symptoms include nicotine cravings, but they also include non-specific things like irritability, change in appetite, sleep trouble, and mood changes things that people might not recognize as nicotine withdrawal

The team from Portland State University experimented with a machine that "inhaled" e-cigarette vapor at low voltage and high voltage to see if and how much formaldehyde was produced by the heating of the vaping liquid, which contains flavoring chemicals, nicotine, propylene glycol and glycerol

And thats really all I know, until I hear back from the school archivist, who may or may not know more than I do

Sources Baron, J.A