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Aim for 64 to 80 ounces of water daily as a baseline, plus an additional glass or two with each creatine dose

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In support of this, ICV administration of GLP-1 in rats has been shown to attenuate the fasting-induced rise in NPY/AgRP expression and decreases fasting-induced inhibition of POMC/CART expression in the ARC (Seo et al., 2008)

Also affect the neurodevelopment of brain cells [156,157]

These medications can be topical (for local infections) or oral (for more widespread or systemic infections)