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Dividing and senescent cells were treated with the peptides, and the cell viability was measured using the MTS assay, with the IC 50 values determined accordingly

Intracellular lipid peroxidation and glutathione levels were quantitatively measured using malondialdehyde (MDA) and GSH assays, respectively

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In line with the importance of TXNRD1 in the regulation of ferroptosis and apoptosis in AML cells, auranofin, a TXNRD1 inhibitor, impaired cell viability in AML subtypes dependent on TXRND1 for their protection against ferroptosis [53]