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These models incorporate spatial and temporal smoothing and a series of county- and state-level covariates to improve predictions for all counties, including those with limited data available in a given year from the BRFSS

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Similar trends of e-cigarette use could occur in our youths and there is a need to prevent e-cigarettes from becoming entrenched in Singapore, given the evidence that e-cigarette use in young non-smokers is associated with future experimentation and use of cigarettes, and the inherent harmfulness of e-cigarettes