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Dual GIP & GLP-1 Agonists While Single GLP-1 RAs focus on one incretin pathway (the GLP-1 pathway), Dual GIP and GLP-1 agonists double down by also acting on another pathway involved in glucose regulation and energy balance

Most available literature addresses initiation or comparative efficacy rather than transition 7

Mistake four: not adjusting diet and supplementation Your nutritional strategy on tirzepatide was calibrated for dual agonist therapy

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Possible Benefits of Combination Therapy More weight loss: Combining bupropion with GLP-1 agonists can lead to more significant weight loss than either medication alone