Known widely as Ozempic face, these changes can leave individuals feeling less confident in their appearance, even as they celebrate weight loss milestones
Raising similar concerns, researchers from Denmark published a study in 2024 looking at bone density in 195 participants given the GLP-1 drug Victoza
Additionally, studies have shown that gastric pentadecapeptide BPC 157 exerts a modulatory influence on angiogenesis during the healing processes of muscle and tendon (Brcic et al
100102 In addition, inflammatory cytokines are reportedly involved in CYP gene expression, with the reduced cytokine levels-mediated by GLP-1 RA administration may alter CYP gene expression, potentially leading to changes in the pharmacokinetics of co-administered drugs (Figure 3)
Furthermore, intramuscular injections carry higher risks, require a longer and thicker needle (which goes against everything we've just discussed), and can be significantly more painful