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8 GIPR deficiency in mice leads to impaired glucose tolerance with reduced cell function, 9 while GIP overexpression results in improved glucose tolerance, enhanced cell function, and resistance to highfat dietinduced obesity

This is one of the main reasons clinician-led protocols exist - a qualified provider can evaluate your full health picture before recommending a dosage

8: Ketterer B, Coles B, Meyer DJ (1983)

Some common side effects of Vitamin B12 include headache, nausea, anxiety, nervousness, diarrhea, swelling, infection, severe itching of skin, loss of coordination and balance

Doctors may perform a test dose to check for sensitivity