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Discovery and identification of late stage selective nonpeptide somatostatin subtype 5 (sst5) agonists for the treatment of hyperinsulinemic hypoglycemia

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Similarly, in patients with MASLD, circulating and hepatic GDF-15 levels were significantly elevated, particularly in those with advanced fibrosis

However, even larger PET MPs (median diameter 85 m) may pose a risk to renal function, as a single oral exposure led to increased serum urea and creatinine levels in Wistar rats [149]

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