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It works by binding to the ghrelin receptor (GHS-R1a) in the hypothalamus and pituitary, triggering a calcium/PKC signaling cascade that releases stored growth hormone, while separately blunting somatostatin's inhibitory signal

J Trace Elem Med Biol Organ Soc Min Trace Elem (GMS)

Improper treatment of vitamin B 12 -dependent megaloblastic anemia with high-dose supplemental folic acid can potentially delay the diagnosis of vitamin B 12 deficiency and thus leave the individual at risk of developing irreversible brain and nervous system damage

In a very practical sense, B12 and other water-soluble vitamins are the safest and easiest nutrients to supplement because your body takes what it needs and gets rid of what it doesnt

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