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Research shows that receiving lipotropic injections on an empty stomach can maximize the results of the treatment

Anecdotes exist of riders finding it harder to fuel, needing to drastically alter nutrition (often away from optimal carb strategies), and struggling with energy levels during hard efforts while on these medications

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This hyperactivity may be due in part to reduced responsiveness of pyramidal neurons to GABAergic inhibitory inputs (272)

The most common side effects include nausea, vomiting, diarrhea, stomach pain, low appetite (which the drug is meant to cause), fatigue, and dizziness