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Important considerations include that this remains off-label use only, insurance coverage for men is not available, fewer safety data exist in male populations, and use should only occur under physician supervision

Measurement of oxidative stress and total antioxidant capacity in hyperthyroid patients following treatment with carbimazole and antioxidant

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This may cause chemical leukoderma, a form of depigmentation that can look very much like vitiligo

[1] The medication carries a boxed warning regarding thyroid C-cell tumors observed in rodent studies and is contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN2)