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This may be attributed to the dimeric structure which hinders enzyme access to active sites, showcasing significant resistance to enzymatic degradation 49,55

Dipeptidyl peptidase-4 (DPP-4) inhibitors in the management of diabetes

Providers review medication interactions and assess cardiovascular risk

In response to external stimuli (e.g., hypoxia, ischemia, drug-induced injury), mTORC1 promotes the translation of HIF-1, thereby driving a metabolic shift from oxidative phosphorylation to glycolysis (Wang et al., 2020)

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