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AMPK is often described as the cells energy sensor: it activates when cellular energy levels drop and triggers a cascade of responses aimed at restoring energy balance and promoting cell survival and proliferation

None of these studies revealed any significant differences between the ASD group and the healthy control group, although it is appropriate to be cautious in interpreting negative findings

McShane et al., 2013

Thus, many treatments that are believed to improve mitochondrial function have been shown to be helpful for some children with ASD

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