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Dehydration concentrates urine and places temporary stress on kidney function, even though the underlying GLP-1 mechanism remains kidney-protective
Wharton, the STEP 5 Study Group, Two-year effects of semaglutide in adults with overweight or obesity: the STEP 5 trial
An overall diet high in healthy fats like olive oil (such as the Mediterranean diet) has been shown to lead to better blood sugar control and increased GLP-1 levels compared to a diet high in saturated fats
Study found that increasing endogenous and exogenous intestinal SCFAs can stimulate intestinal endocrine cells to secrete GLP-1 and PYY by binding to GPR41 and GPR43 (Tian et al., 2024)
To explore how well GLP-1R agonists access various parts of the brain, Sechers team labeled various agonists with fluorescent tags so that when they administered the agonists to mice, they could see which areas of their brains lit up
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