What community members commonly report: Injection-site reactions (redness, swelling) expected with large-volume subcutaneous injections Mild flu-like symptoms in the 24-72 hours following injection, which some interpret as an immune response to senescent cell die-off Fatigue and general malaise lasting 1-3 days post-injection No noticeable positive effects yet What community members probably will NOT notice: Improved energy or vitality Visible changes in skin, hair, or physical appearance Measurable changes in bloodwork Any performance enhancement Realistic expectation: Week 1 is about initiating the senolytic process
Ggebakan O, Kohl A, Osterhoff MA, van Baak MA, Jebb SA, Papadaki A, et al
A statistically significant increase in thyroid C-cell adenomas was observed in males and females at all dose levels, and a statistically significant increase in thyroid C-cell carcinomas was observed in males at 0.01 mg/kg/day, at clinically relevant exposures
Uematsu M, Yoshizaki T, Shimizu T, Obata JE, Nakamura T, Fujioka D, Watanabe K, Watanabe Y, Kugiyama K
This may limit our ability to evaluate whether the observed protective association is mediated by improvements in psychological well-being
