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Brundu S, Palma L, Picceri GG, Ligi D, Orlandi C, Galluzzi L, Chiarantini L, Casabianca A, Schiavano GF, Santi M, Mannello F, Green K, Smietana M, Magnani M, Fraternale A

959 tFNA-Cur also has great potential for treating other diseases related to ferroptosis

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BPC-157 activates the FAK-paxillin pathway, which increases fibroblast migration to injury sites

Future efforts should leverage integrated multi-omics and single-cell sequencing to systematically map the ferroptosis-cuproptosis interactome in OSCC, identify master regulatory nodes, and stratify patients most likely to benefit from such therapies