Common side effects of losartan include: Back pain Knee pain Leg pain Muscle cramps Muscle weakness Heartburn Diarrhea Changes in sensation, such as reduced sensitivity to touch Serious Risks of Losartan and Lisinopril Both lisinopril and losartan share several potential serious risks including: Kidney problems , including worsening kidney function or acute kidney injury Hyperkalemia (high potassium levels), especially in people with kidney disease or diabetes Hypotension (dangerously low blood pressure), particularly in people who are dehydrated or taking diuretics Fetal harm , making both medications unsafe during pregnancy Angioedema (rare but serious swelling of the face, lips, tongue, or throat) ACE inhibitors like lisinopril are more likely to cause a persistent dry cough and have a slightly higher risk of angioedema compared to ARBs like losartan
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A combination of strength training and cardiovascular exercise works best
However, more receptors also means more pharmacological complexity
