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The MHRA safety guidance emphasises that GLP-1 receptor agonists should only be used under medical supervision with appropriate monitoring

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10.1038/s41598-022-10187-y [DOI] [PMC free article] [PubMed] [Google Scholar] Pitkowska-Chmiel I, Herbet M, Gawroska-Grzywacz M, Dudka J (2022b) Regulation of neuroinflammatory signaling by PPAR agonist in mouse model of diabetes

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Yes, you can generally take antibiotics while on semaglutide