Treatment of chronic inflammatory diseases and now COVID-19 appears to be complex and may resist finding a single silver bullet intervention (247) supporting the use of combination therapies (170)
Then, 5 of 29 on the elderly, B-vitamins deficiency may manifest as mood disorders, behavioral disorders, autonomic dysfunction, polyneuropathy and encephalopathy (, )
F., Acha, B
Mathew, R
Current modulation strategies range from conventional approaches, such as antibiotics, probiotics, prebiotics, and synbiotics, to more advanced techniques, including antimicrobial peptides (AMPs), fecal microbiota transplantation (FMT), rumen microbiota transplantation (RMT), phage therapy, synthetic microbial communities (SynComs), and genetically engineered microorganisms (GEMs) 9,10,11,12,13,14,15,16