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Discovery of a novel olefin derivative as a highly potent and selective acetyl-CoA carboxylase 2 inhibitor with in vivo efficacy

First, we test every batch to more than 99% purity by HPLC

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LDL-C was also affected and the statistical significance was evident among the ovariectomized control group and the control group ( p = 0.15 ) as well as among the Anastrazole and control groups ( p = 0.15 ) and Letrozole and control groups ( p = 0.19 )