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Its directly involved in nerve health

But it could be that some cholesterol-lowering drugs make it to the skin and prevent its synthesis

And yes, you can get the metabolizer of progesterone through the topical chamber that they can leave it longer versus if you take it orally, it goes straight to the liver, and breaks everything down to progesterone, and makes it [unintelligible [01:32:35] pregnenolone which binds to GABA receptors, makes you fall asleep