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Triethylamine, triethanolamine (TEA), thionyl chloride, methanol, ethanol, isopropanol, toluene, dichloromethane, N,N-dimethylformamide (DMF), Tween 80, hydrochloric acid (HCl), sodium hydroxide, 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid (HEPES), glycerol, ethylenediaminetetraacetic acid (EDTA), glutathione, magnesium chloride (MgCl 2 ), dithiothreitol (DTT), trichloroacetic acid (TCA), thiobarbituric acid (TBA), potassium dihydrogen phosphate (KH 2 PO 4 ), hydroxylamine hydrochloride, hydrogen peroxide (H 2 O 2 ), ascorbic acid (AsA), bovine serum albumin (BSA), -mercaptoethanol, L-methionine, nitroblue tetrazolium (NBT), riboflavin, Triton X-100, polyvinylpyrrolidone (PVP), guaiacol, and acetic acid were acquired from Sinopharm Chemical Reagent Co., Ltd

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Moreover, H3K27 KMTs enriched at Pdx1 gene (a pancreatic gene) upstream which suppressed the pancreatic development while favored hepatic development (Xu et al., 2011)