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This primed environment not only heightens susceptibility to respiratory infection but also amplifies existing chronic inflammation in conditions like COPD and OSA

Nature Communications , 2026

DPP, Dipeptidyl peptidase

The increase in APP concentration in plasma promotes the production of proteolytic enzymes in the body, resulting in renal endothelial cell damage, endothelial cell permeability increase, glomerular filtration dysfunction, and ultimately aggravate kidney disease, which is often considered to be an important bridge between periodontitis and systemic inflammation

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