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As chronic diseases rise globally, pharmaceutical companies are aligning their research and development initiatives with the World Health Organization's recommendations to combat non-communicable diseases

Disorders of CPT1B, the muscle isoform, and CPT1C, the neuronal isoform, have not been reported in humans yet

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The aromatization hypothesis was first proposed by Naftolin in 1975 (145) and expanded on by others (133, 226)

Thus, our study aims to synthesize pathophysiological evidence of energy metabolism, immune inflammation, and neurovascular system abnormalities observed following physical or cognitive exertion