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The differential diagnosis of amelanotic melanoma includes poorly differentiated carcinoma and lymphoma [13]

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Compounds 102, 103 and 105 were prepared as 5 M solutions and compound 104 and control compound 1 were prepared in 3 M solutions

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Additionally, the applicant asserted that the Uretero1 TM decision makes clear that the lack of such evidence comparing the nominated device to other disposable devices does not and should not preclude an applicant from meeting the substantial clinical improvement standard