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The FDAs approval is based on two phase III trials, ATTAIN-1 and ATTAIN-2
The possible modulatory role of statin therapy on ACs levels concerning CAD prediction was also noted (OR 1.247, 95% CI 0.3182.306, p = 0.004 for the sum of ACs plasma levels, OR 1.480, 95% CI 0.4282.747, p = 0.002 for the sum of short-chain ACs plasma levels, and OR 1.346, 95% CI 0.3592.496, p = 0.003 for the sum of SFA-ACs) but not related to statin type ( p = 0.856) nor high dose therapy ( p = 0.465)
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It is always best to consult with a healthcare provider before using any new skincare products during pregnancy