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doi: 10.3389/fimmu.2025.1666866 Received 16 July 2025 Accepted 06 October 2025 Published 31 October 2025 Volume 16 - 2025 Edited by Silvia Turroni, University of Bologna, Italy Reviewed by Keyu Ren, The Affiliated Hospital of Qingdao University, China Yong Lai, Sichuan Academy of Traditional Chinese Medicine, China Updates Copyright 2025 Yang, Huang, Long and Li