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sitagliptin 50 mg bid with metformin HCl immediate-release 1000 mg bid, -1.9%

The drug is started at a low dose and titrated upwards over several months partly to manage these effects

What if you added cystine to the centre of your formulations

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In a study comparing the two drugs for weight loss, people lost an average of 5.9% of their body weight in three months with tirzepatide, compared to 3.6% with semaglutide