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Furthermore, in vitro experiments using cultured human retinal Muller glia and retinal pigment epithelial (RPE) cells showed that GSNO treatment reduced SA-induced inflammatory mediators and cell death

TMAO levels are also modulated by kidney clearance, and impaired renal function leads to TMAO accumulation, further amplifying cardiovascular risk [4]

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Table 2 Comparison of Spinal MMNST and SSP-MMNST