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Unused injectable versions of semaglutide should be stored in a refrigerator as the liquid medicine is susceptible to degradation and bacterial growth when kept at room temperature until its used

Tirzepatide targets both GLP-1 and GIP receptors, whereas semaglutide only targets GLP-1

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If the increase from 0.5mg to 1.0mg triggers significant nausea, stepping to 0.75mg first can ease the transition

Emerging research suggests these changes can extend beyond the gut itself, affecting the vaginal and urinary microbiomes through what scientists call the gut-vaginal-urinary axis