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It can therefore be concluded that ToxCast PPAR and RXR assays and some of the computational tool predictions available from the US EPA Chemical Dashboard, are suitable for high throughput screening (HTS) in the identification of potential hazards and prioritisation of chemicals from large chemical libraries that could not otherwise be screened in lower-throughput model systems
Alcohol is calorie-dense and may contribute to weight gain, especially when consumed regularly or excessively
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Responsible interpretation requires acknowledging both the strong mechanistic research and the current lack of large-scale human clinical trials for systemic uses
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