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While GPX3 localized mainly to the basement membrane of the bronchial epithelium and endothelium in healthy mouse and human tissue, we found localization also to the interstitial ECM in fibrotic tissue compartments

In cell experiments, zinc oxide nanoparticles significantly elevated the PINK1, Parkin, and LC3 expression levels, promoted autophagosome formation, resulting in cell cycle arrest, and inhibited tumor cell proliferation in diffuse large B-cell lymphoma, potentially explaining their anti-tumor effect

A functional screen for Myc-responsive genes reveals serine hydroxymethyltransferase, a major source of the one-carbon unit for cell metabolism

Moreover, glutathione can also recycle important antioxidants such as vitamins E and C can promote proper immune function

GHK-Cu GHK is a naturally occurring tripeptide that can bind copper ions to form GHK-Cu