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We did not include pediatric patients or geriatric patients older than 70 years, and our cohort was fairly demographically homogeneous, so it is unclear whether our findings are generalizable to various groups

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Post-hoc power calculations (G*Power 3.1) using the reported effect sizes (Cohens d 0.250.40) indicate that 80% power to detect a minimal clinically important difference of 1 cm on the VAS pain scale would require 128200 completers per arm

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