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W jednym z bada 36% pacjentw na tirzepatydzie osigno 15% spadku masy ciaa, podczas gdy na semaglutydzie tylko 8% (The effectiveness and value of tirzepatide for type 2 diabetes mellitus)

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Patients with certain medical conditions should exercise caution: those with Leber's hereditary optic neuropathy (a rare genetic condition) may experience optic nerve damage with high-dose cyanocobalamin