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To exclude a generalized antioxidant effect and establish pathway specificity, we compared mitoTEMPO with NAC, a broad-spectrum intracellular antioxidant

Important Note on the Evidence Base Important note on the evidence base: The preclinical AOD-9604 literature in obese mouse and Zucker rat models is consistent and reproducible

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Anjum et al., 2018)

Consequently, a lack of function of TREM2 has previously been linked to an increased risk of AD [100]