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Although the CR group exhibited significantly lower lumbar spine and hip BMD compared to controls, there were no significant differences in serum CTX, bone-specific alkaline phosphatase (BSAP) levels, or trabecular microarchitecture parameters (e.g., erosion index, surface-to-volume ratio) between the groups

Medical experts emphasise the need for further research to better understand these interactions and ensure safer use, especially for patients taking medications with narrow therapeutic ranges

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