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Environmental oxidative agents are the root cause of exogenous aging, and skin aging triggered by extrinsic factors varies from other tissues aging [109,110]

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The plateau-breaking potential is one of the primary reasons clinicians combine these compounds

Due to the strong cytoprotective effects of GSH, alterations in GSH homeostasis have been associated with neurodegenerative diseases, AIDS, liver and heart disease, aging, diabetes mellitus and cancer (reviewed in [19,20,21])