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10 (1): p
GLAST and GLT-1 act as Glu transporters in glial cells in vivo and are involved in the regulation of Glu concentration in synaptic clefts, whereas EAAC1 is not involved in the regulation of extracellular Glu levels in synaptic clefts, but rather in the regulation of GSH production via extracellular Cys uptake
253 GLP-1 secretion from L-cells increases substantially in response to many cytokines such as interleukin-6, and interestingly, GLP-1 levels are elevated in patients with sepsis and are correlated with the severity of illness and clinical outcomes, although it is currently unclear if the elevation of GLP-1 levels exacerbates or alleviates pathology during sepsis
