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Used at typical food-safe levels with a long regulatory track record

ketoconazole), and protease inhibitors (e.g., ritonavir), can increase the plasma concentration of oxycodone, resulting in increased or prolonged opioid effects

Oral doses can start at 300mg per day and go up to several thousand milligrams if necessary with certain inflammatory conditions

doi: 10.3389/fmicb.2019.01136 Received 13 September 2018 Accepted 06 May 2019 Published 10 June 2019 Volume 10 - 2019 Edited by Vishal Singh, The University of Toledo, United States Reviewed by Konstantinos Papadimitriou, Agricultural University of Athens, Greece