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In addition to various enzymes (e.g., CBS and CSE) in organs, H 2 S is produced by numerous gut microbes, such as Clostridium , Desulfovibrio , Escherichia , Klebsiella , Salmonella , Streptococcus , and Enterobacter 20,21,22

Macronutrient metabolism by the human gut microbiome: major fermentation by-products and their impact on host health

These products can act as agents that not only spread oxidative damage around the body but also modify specific cellular processes [16,17,18]

Toxicol Appl Pharmacol 159:175184 Aravindakumar CT, Ceulemans J, De Ley M (1999) Nitric oxide induces Zn 2+ release from metallothionein by destroying zinc-sulphur clusters without concomitant formation of S-nitrosothiol

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